Volume 36 · Number 1
JANUARY 2006
The Clinical Significance of Psychotic Depression
By Diana Feldman, MD
As reviewed by Rothschild et al. in this issue, studies published during the past 2 decades have demonstrated that major depression associated with psychotic features (MD-Psy), particularly delusions, is associated with poor outcomes, including a greater mortality rate, an increased risk for suicide, and poorer functional outcomes than occur with nonpsychotic major depression. Nevertheless, our knowledge about the pathogenesis and long-term management of MD-Psy remains limited. Greater awareness of this disorder and more accurate diagnoses are required to optimize the treatment response and prognosis of MD-Psy.
ABOUT THE AUTHOR
Dr. Feldman is psychiatry resident, New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, NY.
Address reprint requests to: Diana Feldman, MD, New York Presbyterian Hospital, 525 E. 68th St., Box 140, New York, NY 10021.
What Do We Know and What Don’t We Know?
Jan Fawcett, MD
Psychotic Depression
Barnett S. Meyers, MD
A 38-year-old Man With Anxiety, Intrusive Violent Thoughts
Pharmacotherapy of Major Depression with Psychotic Features: What is the Evidence?
Carmen Andreescu, MD;
Benoit H. Mulsant, MD;
Anthony J. Rothschild, MD;
Alastair J. Flint, MD, FRCPC, FRANZCP;
Barnett S. Meyers, MD;
Ellen Whyte, MD
Challenges in Differentiating and Diagnosing Psychotic Depression
Anthony J. Rothschild, MD;
Benoit H. Mulsant, MD;
Barnett S. Meyers, MD;
Alastair J. Flint, MD, FRCPC, FRANZCP
Research Assessment of Patients With Psychotic Depression: The STOP-PD Approach
Alastair J. Flint, MD, FRCPC, FRANZCP;
Ayal Schaffer, MD, FRCPC;
Barnett S. Meyers, MD;
Anthony J. Rothschild, MD;
Benoit H. Mulsant, MD
Methodological Issues in Designing a Randomized Controlled Trial for Psychotic Depression: The STOP-PD Study
Barnett S. Meyers, MD;
Catherine Peasley-Miklus, PhD;
Alastair J. Flint, MD, FRCPC, FRANZCP;
Benoit H. Mulsant, MD;
Anthony J. Rothschild, MD
